Jmcgh and Other sites: Non-Urine Sites Only

 Numbers are percent susceptible

Gram Negative

 Organisms

No. of

isolates

amk

am/s

cz

fep

caz

cx

esbl

(+)

etp

gm

le

mer

tmp/

smx

Acinetobacter

baumannii

79

-

82

-

39

25

-

-

-

62

33

85

41

Citrobacter

freundii

9*

100

-

0

100

78

89

-

100

89

89

100

78

Citrobacter

koseri

19*

100

-

100

100

100

100

-

100

100

84

100

79

Enterobacter

aerogenes

18*

100

-

0

100

94

94

-

100

100

100

100

100

Enterobacter

cloacae

52

100

-

0

94

74

70

-

92

91

89

100

81

Escherichia

coli

349

99

46

83

90

89

90

10

100

79

49

100

61

Klebsiella

oxytoca

22*

100

96

87

100

100

100

0

100

91

91

100

91

Klebsiella

pneumoniae

129

98

85

90

92

92

92

7

99

95

92

99

85

Morganella

morganii

49

100

0

0

94

63

94

-

100

78

57

100

49

Proteus

 mirabilis

265

100

59

91

98

98

98

-

100

79

35

100

37

Providencia stuartii

28*

100

0

0

100

93

100

-

-

36

21

100

29

Pseudomonas

aeruginosa

323

99

-

-

75

77

-

-

-

72

55

76

-

Serratia

marcescens

34

100

-

0

100

100

100

-

100

97

85

100

94

Stenotrophomonas maltophilia

37

-

-

-

-

-

-

-

-

 

81

-

95

*NO. of isolates-“Percent susceptible for each organism/antimicrobial combination was generated by including the first isolate of that organism recovered from a given patient.” When fewer that 30 isolates are reported it should be noted that less than statistical validity of the estimates of percent susceptibility exist.

 

Abbreviation Key: amk- amikacin, am/s-ampicillin/sulbactam, cz-cefazolin, fep- cefepime, caz-ceftazidime,

cx-ceftriaxone, esbl-Extended Spectrum Beta Lactamase, etp-ertapenem, gm-gentamicin, le-levofloxacin,

mer-Meropenem nit-nitrofurantoin, pip/taz-piperacillin/tazobactam, tmp/smx-trimethoprim/sulfa

 

- antibiotics not tested or not recommended due to lack of correlation between in vitro results and in vivo activity.

 

Comments:

·          66% of Haemophilus infuenzae isolates were beta lactamase negative (97 isolates tested). Beta Lactamase negative indicates probable susceptibility to penicillin, ampicillin and 1st generation cephalosporins. Beta lactamase positive indicates probable resistance to ampicillin, amoxicillin and first generation cephalosporins. Recommended therapy is combination therapy or a third generation cephalosporin.

·          97% of Moraxella (Branhamella) catarrhalis were beta lactamase positive (34 isolates tested). Beta lactamase positive indicates resistance to penicillin, ampicillin and first generation cephalosporins. Several beta-lactams are effective including beta lactam/Beta Lactamase inhibitory combinations, 3rd generation cephalosporins, macrolides, quinolones and trimethoprim/sulfamethoxazole.

·          59 isolates of Salmonella species and 4 Shigella species were recovered. Susceptibility testing is not routinely performed on intestinal sites. Extraintestinal sites are tested against ampicillin, trimethoprim/sulfa and a third generation cephalosporin. Intestinal source isolates will be tested per telephone request.

·          14 Campylobacter species were isolated in 2010.

·          7 Giardia lamblia positive rapid antigens were confirmed in 2010.

·          1 Cryptosporidium positive rapid antigens were confirmed in 2010.