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Penicillin sensitive Streptococcus pneumoniae isolates can be
considered sensitive to ampicillin, ampicillin/sulbactam, amoxicillin/clavulanic
acid, 1st, 2nd, 3rd, and 4th
generation cephalosporins.
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Beta hemolytic Streptococcus species have not
demonstrated resistance to penicillin or ampicillin therefore susceptibility
testing is not routinely performed. Of the Streptococcus agalactiae
performed on isolates recovered from pregnant penicillin allergic women 100%
were Penicillin sensitive, 47% were Clindamycin sensitive and 40% were
Erythromycin sensitive. Erythromycin resistant strains cannot be reliably
interpreted as Clindamycin sensitive without the addition of the "D Test" to
test for inducible resistance.
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